Cyclo-oxygenase-2 contributes to constitutive prostanoid production in rat kidney and brain
نویسندگان
چکیده
منابع مشابه
Cyclo-oxygenase-2 contributes to constitutive prostanoid production in rat kidney and brain.
Cyclo-oxygenases (COXs) catalyse the synthesis of PGH2 (prostaglandin H2), which serves as the common substrate for the production of PGE2, PGD2, PGF(2alpha), prostacyclin (or PGI2) and TXs (thromboxanes). While COX-1 is the major isoform responsible for prostanoid synthesis in healthy tissues, little information is available on the contribution of constitutive COX-2 to the various prostanoid s...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2005
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20050451